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Demonstration Environment

You are entering a simulated instance of the CAR-Tools database. All genomic sequences, affinity scores, and clinical statuses displayed here are mock data generated for demonstration purposes only and do not represent real clinical trials, patient data, or physical biological assets.

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Accession ID Target scFv Length Affinity (Kd) Status Organism

Construct Record: CAR-19-Alpha

Generated via CAR-Tools In-Silico Engine • RefSeq Validated

Summary

Official Symbol
CD19
Primary Status
Phase I Active
Binding Affinity (Kd)
4.2 nM
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Mammalia; Primates; Homo sapiens

Structural Architecture

Hinge Region
CD8α
Transmembrane Domain
CD8α
Co-stimulatory Domain
4-1BB (CD137)
Signaling Domain
CD3ζ

Genomic Sequence (FASTA)

>CAR_scFv_Sequence|Homo_sapiens|synthetic_construct QVQLQQSGAELVRPGSSVKISCKASGYAFSSYWMNWVKQRPGQGLEWIGQIYPGDGDTNYNGKFKGQATLTADKSSSTAYMQLSGLTSEDSAVYFCARRETTTVGRYYYAMDYWGQGTTVTVSSGGGGSGGGGSGGGGSDIELTQSPKFMSTSVGDRVSVTCKASQNVGTNVAWYQQKPGQSPKPLIYSASYRYSGVPDRFTGSGSGTDFTLTITNVQSKDLADYFCQQYNSYPLYTFGGGTKLEIK